{"id":1303,"date":"2021-11-02T13:36:03","date_gmt":"2021-11-02T20:36:03","guid":{"rendered":"https:\/\/shapirolabnew.che.caltech.edu\/?p=1303"},"modified":"2021-12-15T06:25:24","modified_gmt":"2021-12-15T14:25:24","slug":"blowing-up-tumors-from-the-inside","status":"publish","type":"post","link":"https:\/\/shapirolab.caltech.edu\/?p=1303","title":{"rendered":"\u201cBlowing up\u201d tumors from the inside"},"content":{"rendered":"<p><a href=\"https:\/\/shapirolab.caltech.edu\/wp-content\/uploads\/2021\/11\/cavitation.jpeg\"><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-1381 alignleft\" src=\"https:\/\/shapirolab.caltech.edu\/wp-content\/uploads\/2021\/11\/cavitation.jpeg\" alt=\"\" width=\"362\" height=\"181\"><\/a>Congratulations to Avinoam and colleagues on showing that cells can be engineered to migrate into tumors and damage them from the inside upon receiving a focused ultrasound stimulus. Their new paper establishes gas vesicles as genetically encoded seeds for inertial cavitation, bringing together cellular and physical therapy.<\/p>\n<p>Bar-Zion A, Nourmahnad A, Mittelstein DR, Shivaei S, Yoo S, Buss MT, Hurt RC, Malounda D, Abedi MH, Lee-Gosselin A, Swift MB, Maresca D, Shapiro MG*.&nbsp;<strong>Acoustically triggered mechanotherapy using genetically encoded gas vesicles.<\/strong>&nbsp;<em>Nature Nanotechnology<\/em> 16, 1403\u20131412 (2021).&nbsp;<a href=\"https:\/\/www.nature.com\/articles\/s41565-021-00971-8\">article<\/a>&nbsp;|&nbsp;<a href=\"https:\/\/rdcu.be\/cyxtJ\">readcube<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Congratulations to Avinoam and colleagues on showing that cells can be engineered to migrate into tumors and damage them from the inside upon receiving a focused ultrasound stimulus. Their new &hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1303","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/shapirolab.caltech.edu\/index.php?rest_route=\/wp\/v2\/posts\/1303","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/shapirolab.caltech.edu\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/shapirolab.caltech.edu\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/shapirolab.caltech.edu\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/shapirolab.caltech.edu\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1303"}],"version-history":[{"count":3,"href":"https:\/\/shapirolab.caltech.edu\/index.php?rest_route=\/wp\/v2\/posts\/1303\/revisions"}],"predecessor-version":[{"id":1399,"href":"https:\/\/shapirolab.caltech.edu\/index.php?rest_route=\/wp\/v2\/posts\/1303\/revisions\/1399"}],"wp:attachment":[{"href":"https:\/\/shapirolab.caltech.edu\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1303"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/shapirolab.caltech.edu\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1303"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/shapirolab.caltech.edu\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1303"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}