Congratulations to Dan, Mohamad, Brittany and Audrey on their new article in Nature Chemical Biology describing the development of “bacterial thermostats” that allow microbial therapeutics to be controlled remotely using ultrasound, respond to fever, or know when they have exited their host.
Article: Tunable thermal bioswitches for in vivo control of microbial therapeutics.
Press release: Biologists Give Bacteria Thermostat Controls
Video: Scientists Engineer Therapeutic Bacteria to Listen to Us
Congratulations to Hunter, Pradeep, Aadyot, Audrey and our collaborators at Harvard on a new study using NV diamond magnetometry to examine the microscale origins of MRI contrast. A preprint describing this work has been posted on arXiv.
Congratulations to Anupama, Arash, Suchita, Audrey, Ray and David on their cover article in the September issue of ACS Nano! Their work describes how gas vesicles can be engineered at the level of their protein composition and sequence to exhibit new acoustic properties and molecular targeting.
Article: Molecular Engineering of Acoustic Protein Nanostructures
Hermosa Beach, California, July 16, 2016. Thanks to everyone who came!
Congratulations to Arnab, Di and Hunter for their work on aquaporins as a new class of sensitive, metal-free, non-toxic reporter genes for diffusion-weighted magnetic resonance imaging, just posted on bioRxiv. We are also excited to join the digital revolution in rapid dissemination of scientific results, in the footsteps of George Church, Jim Collins, Pam Silver and other early adopters of bioRxiv. More to come!
Beautiful day at the ocean! Corona Del Mar, California, August 1, 2015
Our article on “Genetically encoded reporters for hyperpolarized xenon magnetic resonance imaging” has been published in Nature Chemistry. It describes how the the xenon-binding capabilities of gas vesicles allow them to be detected non-invasively at picomolar concentrations.
Link to the Article
Editor’s Choice in Science Translational Medicine
Thanks to all the lab members, family and friends who joined us for our first annual beach party at Bosla Chica beach!
Our article on the use of microbe-derived gas vesicles as molecular imaging agents for ultrasound has been published.
Link to the Article
News and Views by Mark Borden
Ultrasound movie of injected gas vesicles
Congratulations to everyone involved in this study and our continuing work on genetically encoded and engineered imaging agents for ultrasound!
The Shapiro Lab has officially moved into our newly renovated space in 126 Spalding.